WHAT IS YOHIMBINE A?
Yohimbine, an alpha-2 adrenergic receptor antagonist, is an indole alkaloid found in numerous botanical sources. It is the predominant alkaloid in extracts from the bark of the Pausinystalia yohimbe tree, and can also be found in Rauwolfia root. Yohimbine has two stereoisomers (rauwolscine and corynanthine) that differ little in their physical properties or in their effects on serotonin and dopamine receptors. The three isomers, however, do differ significantly in their affinity for the alpha-1 and alpha-2 adrenergic receptor subtypes. Yohimbine was one of the first radioligands developed for selectively labeling alpha-2 adrenergic receptors.
HOW DOES IT WORK?
Yohimbine works by blocking receptors in the body called alpha-2 adrenergic receptors.These receptors play an important role in inhibiting erections. Therefore, yohimbine is thought to help alleviate erectile dysfunction by blocking the receptors responsible for preventing erections. Yohimbine may also promote the release of nitric oxide. This could lead to the dilation of blood vessels and an increase in blood flow to sexual organs.
Yohimbine is one of the most specific α2A-adrenoreceptor antagonist itself well to antagonism. It is an effective antagonist to xylazine in horses and camels. In horse, yohimbine hydrochloride is an effective antagonist to xylazine sedation in red, fallow. In horse, yohimbine hydrochloride is an effective antagonist to xylazine sedation in red, fallow. In camel, yohimbine has been found to effectively reverse xylazine sedation. Yohimbine overdose does not cause central excitation but instead produces sedation.
Available in 10ml bottles.
ADMINISTRATION AND DOSAGE
Give by intravenous injection only. 1mL/40kg (0.25 mg/kg) bodyweight; mature animals: 1mL/50kg (0.2mg/kg) bodyweight.
Yohimbine A (Hydrochloride) 10mg/ml, contains Parabens
Keep in cool environment. Store below 30°C (room temperature).
Veterinary Use Only.